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Endometrial Cancer

Overview

Endometrial cancer is the most common malignant tumor of the pelvis in women. However, 70% of women at the time of diagnosis, tumor limited to the body of the uterus and possibly a complete cure. Prognosis depends on histologic tumor type and incidence of cancer. Most often the disease begins in postmenopausal women, 25% were younger than 50 years, 5% for age younger than 40 years.

The reasons

According to recent data, cancer of uterine body is hormone-dependent tumors, and the development of this disease is associated with the state hyperestrogenemia (i.e., elevated levels of estrogen in the blood) of endogenous or exogenous origin.

Risk factors are obesity, menstrual irregularities, childlessness, late menopause, anovulation, supplementation containing high doses of estrogen.

Symptoms of uterine cancer

- Bleeding from the genital tract;
- Heavy vaginal discharge with mucus;
- Pain in lower abdomen.

The general condition of the patient usually gets worse only in advanced cases. In general, almost all patients for a long time feel healthy.

Endometrial cancer can spread to the muscle layer up to the serosa of the uterus, in the fatty tissue surrounding the uterus, grow in the vagina, rectum or bladder. Distant metastasis in patients with endometrial cancer most often occurs in the parenchymal organs (lungs, liver) and in the spine.

What you can do?

In 90% of the cases the first symptom of endometrial cancer is bleeding from the genital tract. In this case the value of even a single episode of bleeding. See your gynecologist if any suspicious symptoms. If you are diagnosed with endometrial cancer, do not delay treatment. Follow the advice of doctors. In most cases, the disease responds well to treatment.

What will help the doctor?

Endometrial cancer may be suspected gynecologist with a standard gynecological examination. The doctor will ask you about the complaints, gather a detailed gynecological history. Do not forget to tell your doctor if you take any hormones.

To clarify the diagnosis may require diagnostic curettage of the uterus, endometrial biopsy (inner layer of the uterus), hysteroscopy, or hysterography.

The main treatment for endometrial cancer is surgery combined with radiation therapy. The volume of the operation depends on the prevalence of cancer. As a rule, the operation involves hysterectomy (removal) of the uterus with appendages.
At the present time to improve long-term results using combined therapy with the use of hormonal drugs (synthetic progestins).

Prophylaxis

Prevention of endometrial cancer provides timely treatment of endocrine diseases and the rejection of long-term use of estrogen in high doses for therapeutic purposes. Of great importance are the massive preventive gynecological examinations.